Plant-based biocomplex for bronchopulmonary system: indicator quality parameters, efficiency

Abstract

A new plant - based biocomplex has been developed in the form of dietary supplements for prophylaxis and complex treatment. The biocomplex functional properties are determined by biochemical and pharmacological characteristics of its biologically active ingredients: vitamin A, grape seed extract, licorice root, quercetin, lemon balm herb, birch leaves, Pau Darko bark, anise seeds, plantain leaves, linden flowers, bromelain, vitamin C, mullein flowers, Althea root. Matrix tablet technology is used in the manufacture of dietary supplements. The innovativeness of the technology lies in the structure of the tabletted form, consisting of three types of biomer granules, providing controlled speed and prolonged release of active principles and their targeted delivery. Regulated quality indicators, including nutritional value, mg per 1 tablet are established: ascorbic acid - 25; quercetin - 6.25. The study of safety criteria made it possible to determine the sell-by date of 3 years at a temperature not exceeding 25⁰С, in a dry, dark place. The results of clinical studies serve as evidence of the effectiveness and functional orientation of the developed product including it in the diet of patients with chronic obstructive pulmonary disease (COPD). Test materials indicate a positive effect of dietary supplements on the functional state of the bronchi, immunity, resistance to infectious diseases and the effectiveness of traditional treatment of the bronchopulmonary system. An expert assessment and approbation of a specialized product with the inclusion in the Federal Register of dietary supplements have been made.