Control methods for non-smoking nicotine-containing products
https://doi.org/10.47370/2072-0920-2020-15-4-60-65
Abstract
Non-smoking products for oral consumption are a growing segment of the nicotinecontaining products market and, therefore, the study of the component composition and toxicological load during its consumption is an urgent task. The toxic components of nicotine-containing products are the subject of research in scientific laboratories and are carried out by various methods. Studies have been monitored for potential toxicity determinations of tobacco and non-tobacco smokeless products. The article presents the results of monitoring methods for determining toxic components that determine the risk of nonsmoking products, carried out at the Federal State Budgetary Scientific Institution ARSRCTTP. As a result of the research, methods for the quantitative determination of nicotine content have been determined and the method for the determination of tobacco-specific nitrosamines (TSNA) using high-performance liquid chromatography in the product under study has been validated.
About the Authors
A. G. MirgorodskayaRussian Federation
Alla G. Mirgorodskaya, head of the Laboratory of Tobacco production technology
42 Moskovskaya str., Krasnodar, 350072
M. V. Shkidyuk
Russian Federation
Marina V. Shkidyuk, a senior researcher, Laboratory of Tobacco production technology
42 Moskovskaya str., Krasnodar, 350072
S. V. Kalashnikov
Russian Federation
Sergey V. Kalashnikov, a researcher of the Laboratory of Tobacco Production Technology
42 Moskovskaya str., Krasnodar, 350072
References
1. Shkidyuk M.V., Kalashnikov S.V., Reznichenko I.A. Aerosol generation modes for nicotine-containing products // New technologies. 2020. Issue. 2 (52). P. 89–91.
2. Popova N.V., Perezhogina T.A. Method review // Collection of scientific papers on materials VII International Scientific Conference. Brussel, 2019. P. 76–82.
3. Technical regulations for tobacco products [Electronic resource]: Federal Law No. 268-FL of December 22, 2008. Access mode: http://www.kremlin.ru/acts/bank/28603.
4. GOST R 58553-2019 «Chewing tobacco. General technical conditions».
5. History and practice of nicotine use / Pokrovskaya T.I. [et al.] // Eurasian Union of Scientists. 2019. No. 5-1 (62). P. 58–62.
6. What vaping and electronic cigarette adepts need to know about nicotine / I.V. Moiseev. [et al.]. Access mode: https://pccf.ru/blog/chto-nuzhno-znat-o-nikotine-adeptam-veypinga-i-elektronnykh-sigaret/ (access date: 28/05/2020).
7. Benowitz N.E. Smokeless tobacco as a nicotine delivery device: harm or harm reduction // Clinical Pharmacology & Fheurapetics. 2011.
8. Digard H., et. al. (2013): Nicotine Tob. Res (15) 1: 255–261.
9. GOST 30038-93 (ISO 2881: 77) «Tobacco and tobacco products. Determination of alkaloids in tobacco. Spectrophotometric method».
10. Determination of nicotine in tobacco products by GC / MS [Electronic resource] // CORESTA RECOMMENDED METHOD. No. 87. URL: http://www.coresta.org/.
11. Determination of nicotine in tobacco and tobacco products by gas chromatographic analysis [Electronic resource] // CORESTA RECOMMENDED METHOD. No. 62. URL: http://www.coresta.org/.
12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466669/ (date of treatment 01/20/2020)
13. Determination of tobaccospecific nitrosamines in tobacco and tobacco products by lc-ms / ms «[Electronic resource] // Coresta recommended method. No. 72. URL: http://www.coresta.org/.
Review
For citations:
Mirgorodskaya A.G., Shkidyuk M.V., Kalashnikov S.V. Control methods for non-smoking nicotine-containing products. New Technologies. 2020;(4):60-65. (In Russ.) https://doi.org/10.47370/2072-0920-2020-15-4-60-65